Retinal vein occlusion is commonly associated with vascular risk factors such as hypertension, diabetes mellitus, elevated cholesterol, smoking, and older age, particularly in patients with cardiovascular disease or other cardiovascular risk factors. In younger patients, however, the underlying causes may differ and can include thrombophilic disorders, antiphospholipid syndrome, hyperhomocysteinaemia, autoimmune diseases (such as systemic lupus erythematosus and Behçet’s disease), inflammatory vasculitis, myeloproliferative disorders, use of hormonal contraceptives, glaucoma, or pregnancy. Identifying and managing these risk factors is important for both ocular and overall health. In younger patients, further haematological or rheumatological evaluation may be appropriate depending on the clinical history and findings.